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Cialis History

The FDA Viagra approving on 27 March 1998 was a groundbreaking trade event for the treatment of male erecticle dysfunction, with gross revenue nearly one billion dollars. Subsequently, the FDA authorized Levitra (vardenafil) on 19 August 2003, and Cialis (tadalafil) on 21 November 2003.

Cialis was found by Glaxo Wellcome in collaboration with ICOS. In 1993 ICOS corp. started to examin chemical compound IC351, a phosphodiesterase type 5 (PDE5) enzyme inhibitor. In 1994, Pfizer scientists found out that sildenafil, which also inhibits the PDE5 enzyme, stimulated penial erection in men taking part in a study of a heart medicinal drug. Despite the fact that ICOS men of science weren’t examining chemical compound IC351 for treating male erecticle dysfunction, they realized its prospective usefulness for treating that disease. Shortly, in 1994, ICOS got a license for chemical compound IC351.

In 1998, ICOS Corporation and Eli Lilly and Company settled the Lilly ICOS, LLC, joint venture company to further produce and promote tadalafil as a treatment for erectile dysfunction. Two years after, Lilly ICOS, LLC, registered a New Drug Application with the Food and Drug Administration for chemical compound IC351 (under the tadalafil generic name, and the Cialis trade name). In May 2002, Lilly ICOS claimed that clinical testing proved that tadalafil was in force for up to thirty-six hours, and one year after, the Food and Drug Administration sanctioned tadalafil.

In 2007, Eli Lilly and Company purchased the ICOS Corporation for 2.3 billion dollars. As a consequence, Eli Lilly owned Cialis and shut down the ICOS functionings, closing the joint venture and dismissing a bulk of ICOS’s about five hundred employees, except for 127 employees of the ICOS biologics department, which later was purchased by CMC Biopharmaceuticals.

Individuals surnamed “Cialis” objected to Eli Lilly and Company’s so titleing the medicine, but the corporation has asserted that the drug’s brand name is dissociated to the family name.